SAS | The Power to Know
cq5dam.thumbnail.319.319
White Paper

Use of JMP® for Optimizing a Custom Peptide Microarray to Identify Autoantibodies for Multiple Sclerosis

About this paper

Design of experiment (DOE) was utilized to optimize a peptide microarray to test autoantibodies in serum against various components of the myelin sheath. Incorporating the ideal assay conditions from a single DOE experiment versus multiple sequential experiments resulted in a reproducible serum assay with low variability, low nonspecific background, and a high level of distinction between multiple sclerosis (MS) and normal samples. A minimum set of peptides was found that achieved a sensitivity of 90 percent. Autoantibodies against each individual peptide were elevated in at least 35 percent of the individual MS patients tested.

About SAS 

SAS는 분석 부문의 선두 기업입니다. SAS는 8만여 곳 이상의 기업에 혁신적인 분석, 비즈니스 인텔리전스(BI), 데이터 관리 소프트웨어와 서비스를 제공함으로써, 고객사가 신속하고 정확한 의사결정을 내릴 수 있도록 지원합니다. SAS는 1976년부터 전 세계 고객사에게 ‘THE POWER TO KNOW’에 입각한 서비스를 제공하고 있습니다. THE POWER TO KNOW®.

SAS Profile이 있으십니까? 이 양식을 자동으로 완성하려면 로그인

*
*
*
*
 
*
*
 
 

Back to Top